An illustration of how things get done in India is given in this column by Dr M K Mani who quotes, without comment, the minutes of the authorisation committee which gives permission for non-related transplants. The first set of minutes refuses permission because the donor is 'not motivated, too young, unmarried and not aware of the complications.' The second set of minutes, less than three weeks later, approves the same donor for the same recipient -- stating that both parties have apologised for giving wrong information about the donor's age.

 

 

 

This retrospective review of 1,014 medical and nursing records at two acute hospitals in London found that 10.8 % of patients experienced an adverse event, with an overall rate of adverse events of 11.7% when multiple adverse events were included. About half of these events were judged preventable with ordinary standards of care. A third of adverse events led to moderate or greater disability or death. While some adverse events are serious and are traumatic for both staff and patients, others are frequent, minor events that go unnoticed in routine clinical care and yet together have massive economic consequences. 

 

 

 

This description of the physician-pharmaceutical industry relationship and its impact on physicians' knowledge, attitudes and behaviour is based on analysing the results of internet searches and through interviews with key informants. The author concludes that the doctor-pharmaceutical representative relationship is an accepted one, which begins in medical school and is maintained through regular meetings. These meetings influence the prescribing practices of physicians,  and get them to add the company's drugs to the hospital formulary. "Attending sponsored CME events and accepting funding for travel or lodging for educational symposia were associated with increased prescription rates of the sponsor's medication. Attending presentations given by pharmaceutical representative speakers was also associated with irrational prescribing." The author concludes: "The present extent of physician-industry interactions appears to affect prescribing and professional behaviour and should be further addressed at the level of policy and education." Surely this is an even more severe problem in India.

 

 

 

This essay refers to various studies documenting the physician-pharmaceutical industry nexus, and its influence on prescribing behaviour as well as public perceptions of the sponsor's drugs. The industry directs medical research, it exerts pressure on medical journals to prevent the publication of unfavourable results, and it uses the internet to provide mis-information. What we need is documentation of such practices in the Indian context.

 

 

 

Do health plans affect the kind of care their subscribers get? This US study compared compared the use of coronary angiography after acute myocardial infarction among Medicare beneficiaries who had traditional fee-for-service coverage with the use among Medicare beneficiaries enrolled in managed care plans, studying a total of more than 50,000 people, adjusting for differences in patients' demographic and clinical characteristics for hospitals' characteristics. Care was evaluated according to guidelines proposed by the American College of Cardiology and the American Heart Association. Among the 44 percent of patients in both groups who had class I indications (for which angiography is useful and effective), more fee-for-service beneficiaries than managed-care enrollees underwent angiography. Interestingly, rates of use among patients with class I indications are fairly low in both groups, suggesting that there is room for improving the care of elderly patients with myocardial infarction.

 

 

 

A prenatal test result showing chromosomal abnormalities leaves women and their partners with an agonising decision on whether or not to continue the pregnancy. How can healthcare providers help them?  There is little research on pre-test counselling, the communication of abnormal results, their impact on parents' decision making, or the long-term outcomes of such decisions. Such a situation poses even more challenges to Indian health care providers. This editorial writer comments on a UK-based pilot study on how parents are told that the foetus has a sex chromosome abnormality. The findings: little or inaccurate information is provided; healthcare providers know little about such abnormalities; and the literature is often out of date and conflicting. However, even accurate information may not tell one how a particular child will be affected.

 

Reproductive decisions are complex, influenced by women's values and beliefs and their hopes for the future baby, attitudes toward abortion, desires for biological children, religious beliefs, attitudes toward disability and human variation, social norms about prenatal testing outcomes, practical issues such as money and social support. Healthcare providers must understand what the information means to women and their partners, to enable decision making. If they cannot, they must refer patients to someone who can help. Women learning of an abnormal prenatal diagnosis deserve accurate information and healthcare providers who convey respect, honesty and compassion, not ill-informed suggestions about whether or not to continue the pregnancy.

 

 

 

Is today's bioethics transplanting Western concepts to Asia? Can Asians develop a concept of bioethics based on their traditional cultures? This article argues that Asian bioethicists must develop a bioethics responding to their own cultural contexts. If western principles are adopted, then they must be re-interpreted and even modified, if necessary, in light of Asian beliefs. Asian interest in medical ethics dates back centuries before the West. In the first century AD the Caraka Samhita laid down standards of behaviour for physicians: they should endeavour to relieve patients, should not desert or injure them and should never cause another's death; they should be committed to helping their patients, but should not to tell patients of their terminal illness. The Susruta Samhita refers to the atharvan, a medicine man in a domestic setting, who helped alleviate personal and family crises.

 

Western biomedical ethics literature has identified autonomy, non-maleficence, beneficence, and justice as the four basic principles of medical ethics. These principles will have different applications - especially with the principles of autonomy and justice - in cultural settings where the family or community carry a greater weight than the individual does.

 

To give a concrete example, the rule of informed consent extends to consulting the patient's family before an action is taken. By the same token, justice cannot be defined as straightforward fairness. A person's responsibility to look after his own health should also be considered.