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Oct-Dec2003-11(4)
FROM OTHER JOURNALS
Research
The authors provide details on how drug companies
get messengers such as journalists or patient groups-apparently independent and
highly credible-to promote their products. They suggest that these messengers be
required to reveal conflicts of interest.Burton B et al. Unhealthy spin.
BMJ 2003;326:1205-7
The pharmaceutical industry has become the single
largest direct source of funds for medical research in Canada, the UK and the
US. Conflicts of interest are inevitable because the goals of the industry and
that of academia differ. The author expresses concern about the increasing
control of the industry on the design and publication of clinical trials, as
drugs are prioritised over scientific merit.
Baird P. Getting it right: industry sponsorship
and medical research. CMAJ 2003;168:1267
These articles describe atrocities committed by
Japanese doctors during World War II, the silence among the public and academia
in Japan, and the need for debate.
Tsuchiya T. In the shadow of the past
atrocities: research ethics with human subjects in contemporary Japan. Eubios
Journal of Asian and International Bioethics 2003;13:100-2
Sass HM. Ambiguities in judging cruel human
experimentation: arbitrary American Responses to German and Japanese
experiments. Eubios Journal of Asian and International Bioethics 2003;13:102-4
Thomas, M. Ethical lessons of the failure to
bring the Japanese doctors' to justice. Eubios Journal of Asian and
International Bioethics 2003;13:104-6
Nie JB et al. A call for further studies on the
ethical lessons of Japanese doctors' experimentation in wartime China for Asian
and international bioethics today.
Eubios Journal of Asian and International
Bioethics 2003;13:106-7
This article describes the angry debate generated
by the publication of a study on the psychiatric consequences of abortion in
low-income women. Among the questions: does ideological bias necessarily taint
research? Are those who publish research responsible for its ultimate uses?
Unwanted results: the ethics of controversial
research. CMAJ 2003;169:93
Clinical
This theme issue of the Journal of Medical Ethics
deals with ethical challenges in organ transplants. The following articles are
of particular interest:
This article describes the differences between
non-heart beating dead donor and heart beating dead donor protocols and argues
for defining death when irreversible asystole occurs, with the open admission
that it does not define 'death' but only a moment in the process of dying when
organ retrieval can be allowed.
Zamperetti N et al. Defining death in non-heart
beating organ donors. J Med Ethics 2003;29:182-5
The author argues that the definition of brain
death should be based on 'the irreversible loss of consciousness, which causes
an irreversible absence of the capacity for integrating the main human
attributes with a functioning body'. It should be considered separately from
organ transplants.
In reply, Kerridge et al say that it is only where
vital organs are sought that a diagnosis of brain death is required, and it has
been necessary to legitimise the process of 'donation'. The 'dead donor rule'
should be replaced with a 'good as dead donor rule' so that the process of
'donation' and transplantation becomes more honest and transparent.
Machado C. A definition of human death should
not be related to organ transplants. J Med Ethics
2003;29:201-2
The authors argue against a proposed policy
permitting removal of organs for transplant from dead people irrespective of
their wishes pre-mortem.
Glannon W. Do the sick have a right to
cadaveric organs? J Med Ethics 2003;29:153-6
The author presents arguments on why it is morally
unjustifiable to increase the supply of organs for transplantation by a policy
giving the sick a right to cadaveric organs. Instead he proposes a model of
organ donation as a form of giving back something to the community from which
one has benefited. This action is not obligatory but supererogatory-beyond the
call of duty.
Hamer CL et al. A stronger policy of organ
retrieval from cadaveric donors: some ethical considerations. J Med Ethics
2003;29:196-200
Mandated choice for organ donation respects
individual autonomy more than any of the other strategies. The authors propose
using the Spanish model where transplant coordinators are charged with gaining
the consent of relatives for organ donation by persuasion if necessary.
Individuals who choose not to donate need not justify their decision in a public
investigation.
Chouhan P et al. Modified mandated choice for
organ procurement. J Med Ethics 2003;29:157-62
The authors argue for the use of tissue left over
after diagnosis for educational and scientific purposes.
van Diest PJ et al. Cadaveric tissue donation:
a pathologist's perspective. J Med Ethics 2003;29:135-6
The author points out that the act of asking a
patient or relative for organ donation puts an immense emotional demand on the
doctor who is designated to do so. Acknowledging this as an altruistic act,
rather than dismissing it as part of their job, will support and encourage the
doctors.
Kirklin D. The altruistic act of asking. J Med
Ethics 2003;29:193-5
The author gives reasons based on the Philippine
culture why prisoners should be allowed to donate organs for transplantation and
proposes safeguards to ensure that their vulnerability will not be exploited.
de Castro LD. Human organs from prisoners:
kidneys for life. J Med Ethics 2003;29:171-5
The authors dispute the assumption that genetically
unrelated donors are much more vulnerable to coercion than are related donors,
and hence are more in need of protective regulation.
Choudhry S. et al. Unrelated living organ
donation: ULTRA needs to go. J Med Ethics 2003;29:169-70
In a well-known British case, the relatives of a
dead man consented to the use of his organs for transplant on the condition that
they were transplanted only into white people. The British government panel
condemned all conditional offers of donation and appealed to a principle of
altruism and meeting the greatest need. This paper criticises their reasoning
saying that while this racist condition was wrong, all conditions are not
necessarily so.
Wilkinson TM. What's not wrong with conditional
organ donation? J Med Ethics 2003;29:163-4
The authors propose a market in organs from living
donors. They suggest features to protect exploitation such as a single buyer
such as the National Health Service, donors and recipients must be residents of
the same country, etc. Also they propose adequate compensation to the donor who
is otherwise the only person currently not receiving any.
Charles A Erin, John Harris. An ethical market
in human organs. J Med Ethics 2003;29:137-8
Is selling body parts wrong in itself, irrespective
of the consequences? Will the harm outweigh the benefits? The authors argue that
there is a case for allowing sale of organs, but they also state that a totally
free market could do a great deal of harm.Richards JR. Commentary. An
ethical market in human organs. J Med Ethics 2003;29:139-40
The following two articles deal with human rights
of sex workers:
Sex work is often regarded as a behaviour, not an
occupation. As a result, sex workers are often not involved in discussions of
their conditions of employment.
Loff B et al. Can health programmes lead to
mistreatment of sex workers? Lancet 2003; 361:1982
A rights-based approach should be used to promote
the health of sex workers and not merely to slow down HIV dissemination.
Wolffers I et al.
Public health and the human rights of sex
workers. Lancet 2003;361:1981
The author describes the confusion, anxiety and
errors that occurred in Taiwan during the recent SARS epidemic and raises
ethical questions regarding stigma, quarantine and its effects, professionalism
of the medical staff, penalties for violators of quarantine, etc.
Hsin DH. SARS: an Asian catastrophe which has
challenged the relationships between people in society: my experience in Taiwan.
Eubios Journal of Asian and International Bioethics
2003;13:107-8
This theme issue of the BMJ discusses death and
dying:
Before any legislation is enacted, more research is
needed to explore and represent patients' views on end-of-life care.
Mak YYW et al. Patients' voices are needed in
debates on euthanasia. BMJ 2003;327:213-15
Care for dying patients needs to respect the views
of people from different faiths and cultures.
Neuberger J. A healthy view of dying. BMJ
2003;327:207-8
In decisions to withhold treatment in non-emergency
settings, there is more time available and the patient can be better prepared.
In emergency situations, withholding treatment cannot be done in a controlled
way. The author describes a case in which even a terminally ill patient and
family needed time to prepare for death.
Saunders Y et al. Planning for a good death:
responding to unexpected events. BMJ 2003;327:204-6
The author discusses how concepts about a good
death depend on the extent of secularisation, individualism and how long the
typical death takes. These change over time.
Walter T. Historical and cultural variants on
the good death. BMJ 2003;327:218-20
The best remedy for reducing the risk of diarrhoea
is handwashing with soap. The authors argue that in a partnership with the
private sector to glamourise hand-washing with soap, the government can more
effectively promote hygienic practices while allocating its scarce resources
elsewhere.
Curtis V et al. Water, sanitation, and hygiene
at Kyoto: handwashing and sanitation need to be marketed as if they were
consumer products. BMJ 2003;327:3-4
Health policy
Till date no law has effectively dealt with medical
futility. Courts had generally let the family decide even if medical
professionals stated that the treatment was futile. The authors describe the
steps to be followed in such an end-of-life medical futility dispute.Fine
RL et al. Resolution of futility by due process: early experience with the Texas
Advance Directives Act. Ann Intern Med 2003;138:743-6
In a no-fault liability system the claimant must
show that the medical error was a causative factor in the resultant injury,
irrespective of who is to blame (proof of causation rather than proof of fault).
In this system negligent professionals would not escape punishment.
Gaine WJ. No-fault compensation systems. BMJ
2003;326:997-8
Patients need access to high-quality balanced, and
accurate information in an easily understandable format. However, pharmaceutical
advertising is designed to 'sell' a product, and highlight the benefits while
playing down the risks.
Garlick W. Should drug companies be allowed to
talk directly to patients? NO. BMJ 2003;326:1302-3
The drug industry remains the only industry where
companies are forbidden from communicating with individual customers about their
products, which the industry claims to do in an ethical and scientific manner.
Patients are not always given information about appropriate treatments that are
deemed 'too expensive.' It may cost more but the patient may consider that price
worth paying.Jones T. Should drug companies be allowed to talk directly to
patients? YES. BMJ 2003;326:1302
Interactions between doctors and drug companies can
lead to ethical dilemmas. This article gives an overview of the guidance and
codes of practice that regulate the relationship.
Wager E. How to dance with porcupines: rules
and guidelines on doctors' relations with drug companies. BMJ
2003;326:1196-8
The author describes the debate in the scientific
community and the public about cloning, which centres on whether human cloning
may be facilitated by allowing research on stem cells.
Daley GQ, Cloning and stem cells: handicapping
the political and scientific debates. NEJM 2003;349:211-12
Education
The author argues that the entanglement between
doctors and drug companies is widespread and a culture of industry gift giving
creates entitlements and obligations that conflict with the primary obligation
to patients undermining rational prescribing strategies.
Moynihan R. Who pays for the pizza? Redefining
the relationships between doctors and drug companies. 1: Entanglement. BMJ
2003;326:1189-92
While medical reform groups call for independent
education and sources of information, the drug industry defends the value of its
educational sponsorship to patients and rejects the idea of disentanglement.
Moynihan R. Who pays for the pizza? Redefining
the relationships between doctors and drug companies. 2: Disentanglement. BMJ
2003;326:1193-6
Not only free newspapers for doctors but medical
journals too depend on income from pharmaceutical advertising, which is often
misleading. Editorial coverage can also be manipulated in many ways to give
results that are favourable for the drug companies.Smith R. Medical
journals and pharmaceutical companies: uneasy bedfellows. BMJ
2003;326:1202-5
An article on the ethics of intimate examinations
without consent attracted powerful comment. This summary of rapid responses to
the article notes that almost all those who mentioned it said that it was
unethical and must stop. No one could explain why it endured, only a handful
tried to defend it. A few others, while not defending examination without
consent, wondered why rectal, vaginal and breast examinations were such a
special case. Contrary to this, patients were less likely to share these views.
One respondent suggested that consultants who thought that intimate examinations
were not especially intimate should hand over their own body parts for
examination by medical students. How can we resolve the special ethical pitfalls
surrounding intimate examinations? First, medical students should be taught
using mannequins and volunteers, rather than patients. Second, students and
patients might be more confident (and less embarrassed) if students had a
clearer and better respected place in the medical team, including being covered
by the team's consent procedures. Third, we could teach intimate examinations
only to postgraduates who need to know, not to undergraduates or to
postgraduates who will never need those skills, says a consultant paediatrician.
Finally, perhaps we should stop doing intimate examinations altogether. 'We do
these examinations because we have 'always done them' and their importance is
over-stated.'
Tonks A. Please don't touch me there: the
ethics of intimate examinations. Summary of rapid responses. BMJ
2003;326:1327