Vol VIII, Issue 4 Date of Publication: October 09, 2023
DOI: https://doi.org/10.20529/IJME.2023.022

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Association of funding and conflicts of interest on outcomes reported in published studies of Covid-19

Snehalata Gajbhiye
Chaitali Chindhalore
Ashish Gupta
Ganesh Dakhale
Abstract:

Background: An outbreak of the Covid-19 has led to substantial mortality globally. The entire world is carrying out studies to understand the pathophysiology, clinical features, diagnosis and treatment of Covid-19. We investigated the possible association of type of funding, corporate or academic, and conflict of interests on the outcomes reported in clinical trials on Covid-19.

Methods: Studies containing the keywords “clinical trial” AND “Covid 19” or “Corona” were located by a search on PubMed published between September 2019 to August 2021. Filters were used to select only papers in the English language and on “humans”. The data were analysed using descriptive statistics and the Chi-square test.

Results: We found a significant association between the existence of a conflict of interest and reporting of a positive outcome (X2 value = 18.751, p<0.001). We also found a significant association between industry funding and reporting of a positive outcome (X2 value = 18.041, p<0.001).

Conclusion: We conclude from this study that the presence of conflict of interest and pharmaceutical industry funding is associated with reporting a positive outcome.


Copyright and license
©Indian Journal of Medical Ethics 2023: Open Access and Distributed under the Creative Commons license ( CC BY-NC-ND 4.0),
which permits only non-commercial and non-modified sharing in any medium, provided the original author(s) and source are credited.

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